Conversion between anti-epilectic drugs (AEDs) is frequently necessary in epilepsy care, exposing patients to a risk of incurring adverse effects and reduced quality of life. I am currently being weaned off of Dilantin and on to Keppra XR. I have been taking 200mg to 300mg of Dilantin daily for over 20 years and my seizures have always been well controlled and I have had limited side effects. This Week in FDA History: Under an Act of March 1, 1899, FDA (then the U.S. Department of Agriculture Div. of Chemistry) investigated imported food for adulteration, with violative products subject to refusal of entry. how to keppra to dilantin conversion for The Directorate of Investment and Company Administration (DICA)'s new electronic registry system will start. I did not change from anything to Keppra, but I added it for Headache prevention and more siezure control and over a month later my doctor took me off due to out of control side effects. Compare Dilantin vs Keppra head-to-head for uses, ratings, cost, side effects, interactions and more. Dilantin rated 6.6/10 vs Keppra rated 6.3/10 in overall patient satisfaction. Dilantin rated 6.6/10 vs Keppra rated 6.3/10 in overall patient satisfaction. Seizures are common in patients with gliomas, and phenytoin (PHT) is frequently used to control tumor-related seizures. PHT, however, has many undesirable side effects (SEs) and drug interactions with glioma chemotherapy. Compare Dilantin vs. Keppra, which is better for uses like: Seizures, Epilepsy and Grand Mal. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Keppra 3.1/5 over Dilantin 2.9/5 in overall satisfaction. Dilantin (phenytoin) is very good at treating and preventing seizures, but it has many drug interactions and some serious side effects. Keppra (levetiracetam) is effective for preventing seizures in people with epilepsy and has fewer drug interactions than its alternatives.