The low-dose and high-dose strategies were defined as daily total IV furosemide equal to or 2.5 times the daily oral dose, respectively. Bolus dosing meant an IV bolus every 12 hours. References: 1. Adam F, et al. [2005] Small-Dose Ketamine Infusion Improves Postoperative Analgesia and Rehabilitation After Total Knee Arthroplasty.