Clomipramine Pregnancy Warnings This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus. -Some experts recommend: Use is not recommended. Animal models have revealed evidence of embryotoxicity, reduced litter size, slightly increased stillborn rate, and decreased mean birth rate. For women who are pregnant, imipramine hydrochloride (Tofranil ®) and imipramine pamoate (Tofranil PM ®) may not be safe. This is based on animal studies that looked at the effects of imipramine during pregnancy and a few reports of birth defects in humans. Is imipramine safe to take if I'm pregnant or breastfeeding? Use of imipramine during pregnancy has not been adequately evaluated. Available evidence suggests that imipramine may be excreted in breast milk and may be harmful to the infant. Pregnancy and Antidepressants: Understanding the Risks Few, if any, medications are considered absolutely safe during pregnancy. Research findings on the effects of antidepressants on the growing. Clomipramine and Pregnancy Category C The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. It is not known if imipramine is safe and effective for use in pregnant women. Tell your doctor if you’re pregnant or plan to become pregnant. Imipramine should be used during pregnancy only if. Communities Depression imipramine during pregnancy. Aa. A. A. A. Close Depression Community 10.5k Members imipramine during pregnancy lavenderinscence. I know you aren't doctors, but my OB GYN is just not helping me with this. I don't have a general practitioner (he retired and they pretty much told me to go elsewhere) I did go to see a psychiatrist at the free clinic, but the man hardly. Also known as Antideprin, Imipramin, Imipramine Hydrochloride, Imipraminum, Imizine, Irmin, Melipramine, Tofranil. The hydrochloride salt form of imipramine, a synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. if an antidepressant is prescribed during pregnancy the the choice of drug will take into account the safety of the drug in pregnancy, in addition to its effectiveness, tolerability and adverse effects.