Women who are taking nonsteroidal anti-inflammatory drugs may be inadvertently stopping their ovulation.[1-3] NSAIDs include over-the-counter drugs such as Ibuprofen (Advil, Motrin) Ibuprofen Health professionals may recommend longer-term use. It is known to increase the risk of heart attacks and stroke if taken regularly in high doses for a long time. Hi everyone - question - did any of you avoid taking ibuprofen (advil) between ovulation and when AF should arrive? I suffer from a lot of headaches and migraines and ibuprofen has always worked so well for my headaches. Ibuprofen May Contribute to Male Infertility, Study Says Time Fourteen of the men took two 600-milligram doses of ibuprofen per day for six weeks an amount consistent with what many athletes take to manage aches and pains while the remaining 17 took placebo pills. Infertility is most commonly caused by problems with ovulation, the monthly release of an egg. Some problems stop an egg being released at all, while others prevent an egg being released during some cycles but not others. NSAIDS, Aspirin & Infertility - Journal Abstracts Doctors may not mention this to women who are trying to get pregnant, but the use of non-steroidal anti-inflamatory drugs, including Advil, Motrin and Aleve, and aspirin cause ovulation problems. Infertility Support Group. In vitro fertilization is one of the most common and utilized ways of treating conception problems. This support group is dedicated to those beginning their journey with IVF and needing support. Ovulation pain may occur a few days before or after ovulation. It doesn't necessarily occur at the exact moment the egg is released from the ovary. It doesn't necessarily occur at the exact moment the egg is released from the ovary. Ibuprofen is an anti-inflammatory and fever-reducing medication. It can be used to treat pain and inflammation associated with many conditions such as menstrual cramps, headaches, arthritis, muscle pain,and toothaches. Having a google trying t find out why my ovulation is all out of wack!!! IBUPROFEN!! It can delay and prevent ovulation if take after menstration!!.