Hydroxyzine may be given either with food or on an empty stomach. If your animal vomits or acts sick after receiving the drug on an If your animal vomits or acts sick after receiving the drug on an empty stomach, try giving the next dose with food or a small treat. Hydroxyzine comes as capsules, tablets, a syrup, and suspension to take by mouth. It usually is taken three or four times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. How to use Hydroxyzine Pamoate. Take this medication by mouth with or without food as directed by your doctor, usually three or four times daily. The dosage is based on your age, medical condition. 1. Acta Psychiatr Scand. 1975 May;51(4):285-8. The influence of food on side effects and absorption of lithium. Jeppsson J, Sjögren J. In a cross-over study, 24 mmol of lithium sulphate was given as a single dose in slow release tablets to 30 healthy volunteers fasting and after a standardised meal. What other drugs will affect hydroxyzine (Atarax, Rezine, Vistaril)? Taking this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking hydroxyzine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures. Overview. Vistaril (hydroxyzine) is an antihistamine that decreases certain symptoms, including hives on the skin, sneezing, and runny nose. It reduces the natural chemical histamine in the body. Hydroxyzine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of itching, or hives on the skin. Hydroxyzine seems to help reduce my nausea, although it doesn't have much of an effect on that sick to the stomach feeling. The cruel irony is that I get stomach cramps and diarrhea unless I take this with food. On the bright side, I don't need a lot of food for this; crackers work quite well. If your stomach feels empty all the time while taking hydroxyzine, know that increased appetite is a documented side effect. Blurred vision : If after taking hydroxyzine your vision seems to have blurred, realize that this is a common side effect. Hydroxyzine belongs to a group of medicines known as sedating antihistamines. It is used to relieve itching caused by some skin conditions, such as nettle rash (urticaria). Exposure to substances such as pollen, pet fur, house dust or insect bites can cause some people to produce an excess of a.