Hydrocodone is in a group of drugs called narcotic pain relievers. Acetaminophen is a less potent pain reliever that increases the effects of hydrocodone. Hydrocodone and acetaminophen combination is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. Acetaminophen-hydrocodone oral tablet is available as a generic drug and as brand-name drugs. Brand names: Norco, Vicodin. Acetaminophen-hydrocodone comes as an oral tablet and an oral solution. Find patient medical information for Hydrocodone-Acetaminophen Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. SIDE EFFECTS. The following adverse reactions have been identified during post approval use of hydrocodone and acetaminophen tablets. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. DESCRIPTION. NORCO® (Hydrocodone bitartrate and acetaminophen) is supplied in tablet form for oral administration. Hydrocodone bitartrate is an opioid analgesic and antitussive and occurs as fine, white crystals or as a crystalline powder. Hydrocodone bitartrate and acetaminophen, USP is available in tablet form for oral administration. Hydrocodone bitartrate is an opioid analgesic and occurs as fine, white crystals or as a crystalline powder. Find information about common, infrequent and rare side effects of Hydrocodone-Acetaminophen Oral. Norco (Acetaminophen & Hydrocodone) is used for treating moderate to severe pain. Hydrocodone is a narcotic, while acetaminophen is a mild painkiller. Lortab is another brand available in the market. Acetaminophen is used to relieve mild to moderate pain from headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, backaches, and reactions to vaccinations (shots), and to reduce fever.