Codeine is used to relieve mild to moderate pain. It is also used, usually in combination with other medications, to reduce coughing. Codeine will help relieve symptoms but will not treat the cause of symptoms or speed recovery. Purple drank is a recreational drug which includes a prescription-strength cough syrup used in a manner inconsistent with its labeling and mixed with a carbonated soft drink. Warning This medicine is a strong pain drug that can put you at risk for addiction, abuse, and misuse. Misuse or abuse of Tylenol w/ Codeine (acetaminophen and codeine tablets) can lead to overdose and death. Codeine is used to treat mild-to-moderate types of pain. The most common side-effects are feeling sick, constipation, feeling sleepy, and dry mouth. Codeine is an opioid medication prescribed to reduce physical pain. It can cause feelings of relaxation, drowsiness, confusion, nausea, itchiness and constipation, especially if taken in large doses. Codeine is a pain relief medication. It works by reducing signals from the body to the brain through the central nervous system, meaning you feel less pain. Codeine is an opioid pain medication, sometimes called a narcotic. Codeine is used to treat mild to moderately severe pain. Codeine may also be used for purposes not listed in this medication guide. What about codeine with guaifenesin? Guaifenesin is classified as an expectorant, meaning it can loosen congestion in the throat and chest. It’s given to people to reduce congestion in their chest resulting from allergies, infections or colds. Codeine is a painkiller. It's used to treat pain, for example after an operation or an injury. It's also used for long-standing pain when everyday painkillers, such as aspirin, ibuprofen and paracetamol, haven't worked. Codeine is an opiate used to treat pain, as a cough medicine, and for diarrhea. It is typically used to treat mild to moderate degrees of pain. Greater benefit may occur when combined with paracetamol (acetaminophen) or a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin or ibuprofen. Evidence does not support its use for acute cough.