To get codeine, you need a doctor's prescription. You can buy codeine-containing medications from a pharmacy. Here you will find more information on what codeine is, what it's used for, how it works, its risks and alternative treatment options. CODEINE is a pain reliever. It is used to treat mild to moderate pain. The lowest GoodRx price for the most common version of generic Codeine is around $20.93, 62% off the average retail price of $56.47. Codeine is a painkiller. It's used to treat pain, for example after an operation or an injury. It's also used for long-standing pain when everyday painkillers, such as aspirin, ibuprofen and paracetamol, haven't worked. Before taking acetaminophen and codeine, tell your doctor and pharmacist if you are allergic to acetaminophen, codeine, sulfite, any other medications, or any of the ingredients in acetaminophen and codeine products. It is used to ease pain. What do I need to tell my doctor BEFORE I take Tylenol w/ Codeine? If you have an allergy to acetaminophen, codeine, or any other part of Tylenol w/ Codeine (acetaminophen and codeine tablets). How to use Acetaminophen-Codeine. See also Warning section. Read the Medication Guide provided by your pharmacist before you start taking acetaminophen/codeine and each time you get a refill. It is used to relieve coughing. It is used to ease allergy signs. It is used to ease cold signs. What do I need to tell my doctor BEFORE I take Promethazine and Codeine? Consumer information about the medication ACETAMINOPHEN/CODEINE - ORAL (Tylenol-Codeine No.3, Tylenol-Codeine No.4, Vopac), includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug ACETAMINOPHEN/CODEINE - ORAL. Codeine is an opioid medication prescribed to reduce physical pain. It can cause feelings of relaxation, drowsiness, confusion, nausea, itchiness and constipation, especially if taken in large doses. Codeine may be habit forming. Take codeine exactly as directed. Do not take more of it, take it more often, or take it in a different way than directed by your doctor.