ambien is out of your system in 12 to 24 hours. But within that time frame it can test out as rophynol. This happened to me. I popped for a date rape drug. The half life of Ambien is 2 hours. This means that every 2 hours, half of the previous amount of Ambien in the body disappears. For example, if you took 10mg of Ambien at 10pm, at 12PM 5mg of Ambien will be left in your body. Ambien works quickly (usually within 15 minutes) and has a short half-life of 2 to 3 hours (the time it takes for plasma levels to reduce by half). Ok can Ambien build up in your system and cause weird side effects? I am on 12.5 but trying to get off. I feel weak, uncoordinated and eyes are out of focus. I also have hypothyroidism. I am on 12.5 but trying to get off. To help others get a better understanding of your situation, share individual factors that may affect clearance speed of Ambien such as: your age, dosage you were taking, and how long you had been taking it. Realize that for the majority of users, Ambien (and its metabolites) are unlikely to stay in your system for more than 1 day after your final dose. However, there will be slight variation. If so, how long does Ambien stay in your system? We'll try and demystify everything, so you can make an informed decision. We'll try and demystify everything, so you can make an informed decision. What Is Ambien and Can It Be Detected? You can multiply the half-life of your medication by a factor of five to determine how long the drug will remain in your system. Certain types of sleeping aids will leave your body within hours after the last dose, while others can stay in your urine, hair and blood for several weeks after quitting. In general, there should not be any traceable amounts in your system after a month of recovery. For most individuals, Ambien will be completely out of the system within 14 hours of use. However, Ambien use remains detectable for much longer, depending on a variety of factors and the type of testing administered. Restoril (temazepam) is in a class of drugs called benzodiazepines, which are central-nervous-system depressants and controlled substances. Restoril is typically prescribed as a short-term sleeping aid to treat insomnia for no more than 10 days and it works by slowing activity in your brain. How long till all the meds get out of your system? I'm sure it's individual, but that's my story. Good luck with yours. I'm sure it's individual, but that's my story. Good luck with yours.