Famotidine is a histamine-2 blocker that works by decreasing the amount of acid the stomach produces. Famotidine is used to treat and prevent ulcers in the stomach and intestines. Famotidine is a white to pale yellow crystalline compound that is freely soluble in glacial acetic acid, slightly soluble in methanol, very slightly soluble in water, and practically insoluble in ethanol. Antacids are medications that increase the pH balance in your stomach. A number of symptoms, including heartburn, gastritis, and gastroesophageal reflux disease (GERD), can be treated with them. DUO Fusion™ chewable tablets combine the antacids calcium carbonate and magnesium hydroxide with the acid reducer (H2 blocker), famotidine. Calcium carbonate and magnesium hydroxide relieve heartburn by neutralizing acid in the stomach. Famotidine, sold under the trade name Pepcid among others, is a medication that decreases stomach acid production. It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. It is taken by mouth or by injection into a vein. It begins working within an hour. HOW SUPPLIED. Famotidine/Heartburn Relief/Pepcid/Pepcid AC/Pepcid AC Maximum Strength Oral Tab: 10mg, 20mg, 40mg Famotidine/Pepcid Intravenous Inj Sol: 1mL, 10mg, 20mg, 50mL Learn about Pepcid (Famotidine) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Fried on famotidine vs omeprazole.To what will help with a distended abdomen depends entirely on the cause of the distention. Probiotics are helpful with a lot of digestive issues, if you take them regularly. The two meds you mention reduce stomach acid and are. Pepcid is the brand name for famotidine, a drug that works to reduce the amount of acid your stomach produces. It's available as both a prescription medicine and an over-the-counter (OTC) medicine. Quickly relieve heartburn associated with acid indigestion and sour stomach with Pepcid Complete Acid Reducer + Antacid Chewable Tablets. These berry-flavored chewable tablets combine a fast-working antacid and a long lasting acid reducer to help control acid all day and night.*.