Learn about Estrace (Estradiol) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. User Reviews for Estradiol. Also known as: Alora, Climara, Estradiol Patch, Menostar, Minivelle, Vivelle-Dot. The following information is NOT intended to endorse drugs or recommend therapy. Estradiol Patch official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. Estradiol is a female sex hormone that fluctuates in concentration and can be used as a good indicator of fertility problems or changes to a woman's menstrual cycle. Learn about Climara (Estradiol Transdermal) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Clinical Significance. Measuring the circulating levels of estradiol is important for assessing the ovarian function and monitoring follicular development for assisted reproduction protocols. Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. PRESCRIBING INFORMATION. Femring ® (estradiol acetate vaginal ring) WARNING: ENDOMETRIAL CANCER, CARDIOVASCULAR DISORDERS AND E2 levels in children, postmenopausal women, and men are much lower than in women of reproductive age. The increased sensitivity and specificity that are achieved by LC/MS-MS are the more appropriate choice for these clinical situations than the electrochemiluminescence immunoassay (ECLIA) method. 1,2 See Estradiol, Sensitive, LC/MS [140244]. ESTRACE® Cream (estradiol vaginal cream, USP, 0.01%) WARNING: ENDOMETRIAL CANCER, CARDIOVASCULAR DISORDERS, BREAST CANCER and PROBABLE DEMENTIA.