Find information about common, infrequent and rare side effects of Simvastatin Oral. I am taking am a 60 yr young diabetic and take Simvastatin. After taking it for awhile I have developed a cough that keeps me up all night and is hard to control. Cough medicines may interact with your statin drugs, affecting their ability to lower cholesterol levels. Ask your doctor what kind of cough medicines are safe to take or whether he has other solutions for your statin cough. Can Atorvastatin cause Cough? Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. Simvastatin belongs to a group of medicines known as statins. It regulates the amount of cholesterol and other lipids made by your body, and helps to reduce the risk of heart and blood vessel disease. Along with its needed effects, simvastatin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. The manufacturer's product labeling should always be consulted for a list of side effects most frequently appearing in patients during clinical studies. The table highlights the cases of iatrogenic cough relative to the administration of atorvastatin, simvastatin, rosuvastatin, fluvastatin, cerivastatin, mevastatin and pitavastatin. Within the considered period, about 9 years, we found 977 spontaneous reports of cough associated with the use of statins. Statin drugs (simvastatin for example) are commonly used to treat high cholesterol and have many known side effects. but here's another. Statins are now believed to potentially cause a chronic dry cough according to a recent report!.