Motrin. Both Motrin and its brand name product Ibuprofen are both non-steroidal anti-inflammatory drugs which can successfully help in treating a large range of different pains. One of the side effects of Ibuprofen is drowsiness. While not everyone will experience that side effect, some are likely to. If you have an allergy to ibuprofen, aspirin, NSAIDS, or any other part of this medicine (ibuprofen tablets). If you are allergic to any drugs like this one, any other drugs, foods, or other substances. One 200mg tablet. it can't be hitting her that hard, can it? You know, once she gets something into her thick blonde head she believes it forever, so I'm thinking she thinks it's suppose to make her sleepy, which is why it does. Placebo effect. Does ibuprofen 800mg make you sleepy Ibuprofen 800 mg tablets All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. Advil® = Ibuprofen is one of the Non-steroidal anti-inflammatory drug often used against pain and/or inflammation, in Ibuprofen Side Effects in Detail - Drugs.com drowsiness is listed as as a symptom of an overdose, although I personally have never seen it in a patient, dizziness is more commonly seen, and of course the most notorious side effect is stomach pains/erosions/bleeds. One of the side effects of Ibuprofen is drowsiness. While not everyone will experience that side effect, some are likely to. share with friends. Share to: Does co-amoxiclav make you sleepy? I'm. Tiredness is one of the side effect of Ibuprofen. As you already said you take it to reduce your menstrual cramps and I think it is normal to take rest or sleep after. I think your body, since in pain, requires resting and sleep in order to recover. Doctors give unbiased, trusted information on whether Advil can cause or treat Drowsiness: Dr. Ibrahim on does ibuprofen make you drowsy: Not usually , if you take only acetaminophen, but sometimes this medicine come as part of other medications like tylenol 3 or 4 or vicodin, then will cause drowsiness.