Metabolism of statins: atorvastatin, cerivastatin and simvastatin is by cytochrome P450 3A4; also cerivastatin is metabolised via cytochrome P450 2C8 CoQ10 Benefit dosage statin drug use and side effects Use with statins such as Lipitor and Zocor Coenzyme Q10 dosage for cholesterol, high blood pressure and heart failure What are statins? Read about the side effects and grapefruit interactions with cholesterol-lowering drugs like Lipitor, Lescol, Mevacor, Pravachol, Zocor, and Crestor. I came across this website and am a little relieved that find other people that understand my symptoms. I had my first episode last september and they went away after taking a short cycle of prednisone. Warfarin and bleeding, side effects, safety, danger and risk, use and interactions with natural supplements, herbs and vitamins, nutritional pills by Ray Sahelian, M.D. Crestor is contraindicated: - in patients with hypersensitivity to rosuvastatin or to any of the excipients. - in patients with active liver disease including unexplained, persistent elevations of serum transaminases and any serum transaminase elevation exceeding 3 times the upper limit of normal (ULN). Coadministered Drug Dose of Drug Dose of Darunavir Effect on Drug Levels Effect on Darunavir Levels Potential Clinical Effects Mechanism of Interaction RxList Articles. Warfarin Source: RxList Medscape. Warfarin is used to treat blood clots and/or to prevent new clots from forming in your body. Learn about side effects, drug interactions, dosages, warnings, and more. Drug. Interaction. Comments. Antacids (aluminum hydroxide- and magnesium hydroxide-containing) Substantially decreased rosuvastatin peak plasma concentration and AUC following simultaneous administration; less substantial decreases when antacid administered 2 hours after rosuvastatin 1 For the treatment of hypercholesterolemia, including hyperlipidemia, hyperlipoproteinemia, or hypertriglyceridemia, as an adjunct to dietary control.