Managing Palmoplantar Disorders Palmoplantar pustulosis. Palmoplantar pustulosis is a chronic pustular condition affecting the palms and soles. What is the cause of palmoplantar pustulosis? Various types of chronic liver injury can cause fibrosis (see Table: Disorders and Drugs That Can Cause Hepatic Fibrosis). Self-limited, acute liver injury (eg, acute viral hepatitis A), even when fulminant, does not necessarily distort the scaffolding architecture and hence does not cause fibrosis, despite loss of hepatocytes. Systemic autoimmune diseases, also known as systemic inflammatory diseases, are inflammatory syndromes involving at least two organ systems. Classical systemic inflammatory diseases include connective tissue diseases, vasculitis, and granulomatous diseases (table 1) [1]. Cardiac involvement is not Evidence suggests that mesenteric panniculitis is an autoimmune disorder. Autoimmune diseases occur when the body’s natural defense mechanisms such as antibodies and lymphocytes, (that are normally in place for prevention of infectious diseases and cancer), instead cause a reaction and damage to the patient’s own healthy tissue. ABSTRACT: Acute pericarditis is the most common form of pericardial disease that results in the need for empirical anti-inflammatory treatment. Cutaneous small-vessel vasculitis, also known as hypersensitivity vasculitis, cutaneous leukocytoclastic vasculitis, hypersensitivity angiitis, cutaneous leukocytoclastic angiitis, cutaneous necrotizing vasculitis and cutaneous necrotizing venulitis, is inflammation of small blood vessels (usually post-capillary venules in the dermis. Gluten and Autoimmune Diseases – Is there a connection? New Research Links Gluten Sensitivity to Multiple Autoimmune Diseases. Research continues to link the autoimmune spectrum of diseases to gluten sensitivity. Colchicine for gout attacks. Colchicine is a prescription drug (Brand Name: Colcrys) that treats gout extracted from plants of the genus Colchicum, a very poisonous plant with no know antidote and known for its’ toxicity. Pericarditis is inflammation of the pericardium, often with fluid accumulation. Pericarditis may be caused by many disorders (eg, infection, myocardial infarction (MI), trauma, tumors, metabolic disorders) but is often idiopathic. Colchicine toxicity has been linked to renal function and it has generally been advised to adjust colchicine dosing in patients with renal insufficiency.