Clotrimazole, sold under the brand name Canesten among others, is an antifungal medication. It is used to treat vaginal yeast infections, oral thrush, diaper rash, pityriasis versicolor, and types of ringworm including athlete's foot and jock itch. It can be taken by mouth or applied as a cream to the skin or in the vagina. DRUG CLASS AND MECHANISM: Miconazole is an anti-fungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). It is used either on the skin or in the vagina for fungal infections. Miconazole was approved by the FDA in 1974. Compare Clotrimazole vs. Ketoconazole, which is better for uses like: Itching, Yeast Infection and Rash. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Ketoconazole 3.9/5 over Clotrimazole 3.6/5 in overall satisfaction. - Page 3 Compare Clotrimazole vs. Ketoconazole, which is better for uses like: Itching, Yeast Infection and Rash. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Ketoconazole 3.9/5 over Clotrimazole 3.6/5 in overall satisfaction. It comes as a mouth gel, cream, vaginal pessaries, and vaginal cream. This medicine is from the same family of solutions as itraconazole, ketoconazole, or fluconazole, that are used mostly in yeast diseases. HI. I have an 11 year old that was prescribed ketoconazole 2% cream for a ringworm infection. I saw where the cream is not evaluated for use in children less than 12 years old. I am just checking the make. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Khanna on clotrimazole vs miconazole: Both products are antifungals. Though chemically different, they are both FDA approved and prescribed to treat jock itch and athlete's foot. Treats fungal infections. Nizoral (Ketoconazole) is a medication used on your skin to treat fungal infections; however, it takes several weeks for full recovery, and the directions are specific to each type of medication. Introduction. The incidence of topical fungal infections has progressively increased in recent years primarily because of an increased number of immunocompromised patients and the increased use of health clubs and community swimming pools, which favour the spread of infections [1,2].