Clemastine, also known as meclastin, is an ethanolamine-derivative, first generation histamine H1 antagonist (antihistamine) with anticholinergic properties (drying) and sedative side effects. Acrivastine is a medication used for the treatment of allergies and hay fever. It is a second-generation H1-receptor antagonist antihistamine (like its base molecule triprolidine) and works by blocking histamine H1 receptors. The main purpose of this study is to assess clemastine as a remyelinating agent in patients with relapsing forms of multiple sclerosis. The study will also evaluate the tolerability of clemastine, originally approved as first-generation antihistamine, in patients with multiple sclerosis. Antihistamines are a group of medications which can inhibit various histaminic actions at one of two histamine receptors (H 1 or H 2). H 1 receptor antagonists are used for the relief of allergic dermatological and nondermatological conditions. Tavist (clemastine) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. La doxylamine est un antihistaminique H 1 (Histamine H1 receptor (en)) de première génération ; il est utilisé pour le traitement des allergies, des insomnies légères ainsi que des nausées induites par la grossesse [3] (considéré hors AMM en france). Drugs.com Mobile Apps. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Pregnant women commonly use over-the-counter medications. Although most over-the-counter drugs have an excellent safety profile, some have unproven safety or are known to adversely affect the fetus. An antihistamine is a type of medicine used to treat common allergy symptoms, such as sneezing, watery eyes, hives, and a runny nose. According to the American College of Allergy, Asthma. Chlorpheniramine maleate, although referenced to the BNF guidance regarding breast feeding and pregnancy below, is not explicitly mentioned in any of the BNF guidance and can be used with caution in these circumstances.