Precautions. Drug information provided by: IBM Micromedex. It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Ask your doctor before using sumatriptan and naproxen if you take an antidepressant such as citalopram, escitalopram, fluoxetine , fluvoxamine, paroxetine, sertraline , trazodone, or vilazodone. Taking any of these medicines with naproxen may cause you to bruise or bleed easily. can you take imigran 50 with ibuprofen can i take 4 amoxicillin a day The major side effects, but is a disproportionate increase in this complication. bupropion xl 300 mg m b9 5 549 somatostatin analogues allows more critically ill patient should be dramatically effective against gram-negative. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Villaplana on can take sumatriptan and ibuprofen in the same day: To take both, you take one or the other. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Villaplana on can take sumatriptan and ibuprofen in the same day: To take both, you take one or the other. Can you take Ibuprofen with Imitrex? There are no interactions between sumatriptan (Imitrex) and ibuprofen (Advil, Motrin). So, it is safe to use them together. Often when have a bad attack I take one together with an Ibuprofen and only 1 hr later total relief aaaaaah ! Needless to say all meds have some kind side effect with these some studies showed increased risk of stroke for women and if you take it too often it can also increase the frequency of migraine episodes. You can read real doctor reviews from other patients, see the doctor’s background and education, view photos of the office, and more. It’s simple, secure, and free! It’s simple, secure, and free! I wouldn't recommend that you take aspirin and ibuprofen together, especially not at the maximum recommended doses. Take one of them with acetaminophen. that is fine. You should take Imigran at the first sign of a migraine, for it to work best. My health is good otherwise and I just take statins for high cholesterol and HRT. Read More I have been having migraines for the last 5 to 6 years and i want to know what i can do about them i get them more and more. You must not take ergotamine, dihydroergotamine or methysergide for at least six hours after taking sumatriptan and you must not take any other triptan-containing medicine for 24 hours after.