Bupropion is an antidepressant medication used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects. Bupropion is an antidepressant used for smoking cessation and to treat a variety of conditions, including depression and other mental/mood disorders. Antidepressants can help prevent suicidal. WARNINGS: Bupropion is an antidepressant used for smoking cessation and to treat a variety of conditions, including depression and other mental/mood disorders. Seeing ghost tablets in the stool is a fairly common occurrence for many different medications but can certainly be alarming. Ghost tablets are simply the intact remnants a pill or tablet that have made it through your digestive tract. Bupropion (bupropion XL, Wellbutrin XL, budeprion XL) is a moderately priced drug used to treat depression. This drug is slightly more popular than comparable drugs. Detailed drug Information for bupropion. Includes common brand names, drug descriptions, warnings, side effects and dosing information. When the shell housing the active drug does not disintegrate or does not get digested, it is passed out in the stool intact as a ‘ghost pill’. This can be a source of anxiety provoking experience and paranoia to patients, carers and professionals alike if the phenomenon is not known and the issue not handled sensitively as the following two cases illustrate. Bupropion (Aplenzin, Wellbutrin, Wellbutrin SR, Wellbutrin XL) is used to treat depression. Bupropion (Aplenzin, Wellbutrin XL) is also used to treat seasonal affective disorder (SAD; episodes of depression that occur at the same time each year [usually in the fall and winter but rarely may occur in the spring or summer months]). Bupropion (bupropion XL, Wellbutrin XL, budeprion XL) is a moderately priced drug used to treat depression. This drug is slightly more popular than comparable drugs. Seeing unabsorbed medications in your stool does not necessarily mean that there is anything wrong with your colon or digestion. Pharmaceutical companies make many different types of medication coatings from extended release coatings to cellulose capsules.