Yes, all opioids are alkaline, which means that they absorb faster and more efficiently in a basic environment(IE: high ph) A @visceral: I can't read your last message, but if your at a point where 3mg made you feel normal, I would take 2ng today, and go from there. The best way to take oxycodone, whether it b percocet, percodan, roxicet, roxicodone, or oxycontin is to crush/chew & swallow the pill, PERIOD. ( CWE if large doses of Acetaminophen are in combination with Some1 Who Aint You's desired Oxycodone dose) what is the best way to detox from oxycodone?? deserveshappiness I have been taking oxycodone regularly since the birth of my son 8 months ago from my severe back pain due to how much weight i gained while pregnant. This Site Might Help You. RE: What is the best way to take oxycodone? I just had a very major oral surgery. I got Watson 933 pills prescribed. 'Best High in the World' by OrsonXL Modern humans must learn how to relate to psychoactives responsibly, treating them with respect and awareness, working to minimize harms and maximize benefits, and integrating use into a healthy, enjoyable, and productive life. Oxycodone is an opioid pain medication sometimes called a narcotic. Oxycodone is used to treat moderate to severe pain. The extended-release form of oxycodone is for around-the-clock treatment of pain and should not be used on an as-needed basis for pain. There is no best way. Some people get very high off 10 MG. So you could split it in 3 highs. Some people need 15-20mg so you could do that then finish the 10 to draw it out. I think he cut me down way to drastically for the tapering to work. I am very disiplined about not taking more than directed I even gave them to my fiance to dispence. Hoever I get migranes from vicodin, and I think cutting me down so fast isnt really the answer.